UBC Okanagan mapped the enzymes that make mitraphylline — but that doesn’t mean a drug or mass supply is imminent
UBC Okanagan researchers have identified the two plant enzymes that assemble mitraphylline’s distinctive spirooxindole architecture, a necessary first step toward…
With FDA Fast Track, Coya’s COYA 302 advances to a make-or-break Phase 2 readout expected in early 2027
Coya Therapeutics’ investigational ALS therapy COYA 302 has been granted FDA Fast Track designation while the randomized, double‑blind ALSTARS Phase…
When optimism bias meets viral nutrition claims: pick a starting point that won’t backfire
People commonly rate their own diets as healthier than they are — a mental shortcut called optimism bias — and…
Biocatalysis vs brute-force chemistry: how Merck made enlicitide decanoate producible as the first oral PCSK9 candidate
Merck published a Science paper describing a new, scalable biocatalytic synthesis for enlicitide decanoate — an investigational oral PCSK9 inhibitor.…
Naked mole rat HAS2 in mice: a proof-of-concept that raises clear checkpoints for human translation
Researchers at the University of Rochester inserted a naked mole rat version of the HAS2 gene into mice, raising tissue…
Restoring a mouse’s youthful gut microbes reversed liver aging and blocked tumors by suppressing MDM2
New experiments at the University of Texas Medical Branch show that returning each mouse’s own preserved youthful gut bacteria to…
Lubiprostone’s kidney signal: increased bacterial spermidine protects mitochondria and slows eGFR loss
Lubiprostone — a common prescription for chronic constipation — slowed decline in kidney function in moderate chronic kidney disease (CKD)…
When BLV appears in breast tissue — interpreting the Texas 59% finding and realistic next steps
Multiple international studies now show bovine leukemia virus (BLV) DNA is detected more often in breast cancer tissue than in…