Blocking Ant2 reprograms T cells — not starves them — and strengthens tumor control in mice
Blocking the mitochondrial ADP/ATP carrier Ant2 does not simply “turn off” T cells. In preclinical work led by Prof. Michael…
Can You Keep Potatoes in a Blood‑Sugar Plan? Cool, Portion, Pair — and When to Stop
You don’t have to ban potatoes to manage blood sugar, but you do need a clear trade-off: use cooling, portion…
Should You Follow NutritionFacts.org’s Daily Dozen? Practical start points, progression, and check signals
NutritionFacts.org is a nonprofit, ad-free platform that translates peer-reviewed nutrition research into practical tools centered on whole plant foods. This…
Recent rat studies mapped an lPBN astrocyte “fullness” switch via glutamate — next checkpoints for translation
New experiments in rats show that activating astrocytes in the lateral parabrachial nucleus (lPBN) sharply reduces food intake through glutamate…
Oral semaglutide vs orforglipron: what ORION’s indirect comparison tells clinicians and patients now
The ORION analysis from Novo Nordisk used population-adjusted indirect comparison methods to contrast oral semaglutide 25 mg tablets with Eli…
OTOF gene therapy restored hearing after one inner‑ear injection in a 10‑patient trial — who it helps and what comes next
A single inner‑ear injection of AAV‑mediated gene therapy that replaces the defective OTOF gene restored measurable hearing in all ten…
CK1 inhibitors protect human cone photoreceptors in a 2,700‑compound organoid screen — safety and delivery are the next hurdles
A large-scale screen using 20,000 human retinal organoids with GFP-labeled cones found that inhibiting casein kinase 1 (CK1) consistently protected…